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Antigens

Antigen List

14-3-3 sigma
26S proteasome non-ATPase regulatory subunit 4
2F7
30S ribosomal protein S3
5-bromo-2′-deoxyuridine BrdU
6XHis peptide, linear
8-oxoguanine DNA glycosylase
A6 Antigen in Biliary Epithelial & Oval cells
Abdominal-B homeobox protein
ABP2 olfactory binding protein
Abrupt
acetylcholine nicotinic receptors, muscle
acetylcholinesterase
Achaete protein
acinar, exocrine gland
Acj6
actin
actin associated antigen, migration-related
actin binding protein 34 (ABP34)
actinin, alpha-
actinin, smooth muscle alpha
Actinomyces naeslundii and oris
Actinomyces naeslundii, oris and israelii
Actinomyces oris
Activating transcription factor 7; ATF7
addressin (PNAd)
adducin-related protein
adenovirus type 5 hexon (human)
ADP-ribosylation factor-like protein 8
Aggregatibacter actinomycetemcomitans
Aggregatibacter actinomycetemcomitans serotype a
Aggregatibacter actinomycetemcomitans serotype a‰
Aggregatibacter actinomycetemcomitans serotype b
Aggregatibacter actinomycetemcomitans serotype c
Aggregatibacter actinomycetemcomitans serotype d
Aggregatibacter actinomycetemcomitans serotype e
Aggregatibacter actinomycetemcomitansserotype d
agrin
Aldo-keto Reductase Family 1 Member B1
Aldo-keto Reductase Family 1 Member C1
Aldo-keto reductase family 1 member C2
alkaline phosphatase isoenzyme
alkaline phosphatase, bone and liver
allatostatin (Ast7)
alpha sarcoglycan
alpha2bBeta3
alpha-2-macroglobulin receptor
alpha-L-fucosidase
aminopeptidase N
ANAPC2; Anaphase promoting complex subunit 2
Anaphase promoting complex subunit 2
angiotensin converting enzyme
Ankyrin repeat and BTB (POZ) domain containing 1
Ankyrin repeat and KH domain containing 1
Ankyrin repeat and zinc finger domain containing 1
Annexin A1 (Annexin I)
Annexin A1 Peptide 1
Annexin A4 Peptide 1
annexin I
annexins I and II
Antennapedia protein
Anti-silencing function 1A histone chaperone
AP-2 alpha
AP-3 (delta subunit)
APA-2 amino acids 618-925
APEX Nuclease I
apoptotic marker in phagocytic cells (nematode)
Aprataxin and PNKP like factor
argos-gene product
ARID3A; AT rich interactive domain 3A (BRIGHT-like)
Armadillo Drosophila protein
Aryl hydrocarbon receptor nuclear translocator-like protein 1
Aspergillus flavus isolate 93803
ASPL-TFE3 type 1
ASPL-TFE3 type 2
AT rich interactive domain 2 (ARID, RFX-like)
AT-hook-containing transcription factor
Atox1
ATPase family AAA domaining containg 2
ATPase family, AAA domain containing 2
ATPase family, AAA domain containing 2; ATAD2
ATPase, (Na (+) K(+)) alpha subunit
ATPase, (Na(+) K(+)) alpha-1 subunit
ATPase, (Na(+) K(+)) alpha-1 subunit (avian)
ATPase, (Na(+) K(+)) beta-1 subunit (avian)
ATPase, (Na(+) K(+)) beta-subunit
ATPase, Ca(+2) fast twitch SR (avian) / SERCA1
ATPase, Ca(+2) fast twitch SR / SERCA1
ATPase, Ca(+2) slow twitch/cardiac SR (avian), SERCA2
ATRX; Alpha thalassemia/mental retardation syndrome X-linked
autoimmune double stranded DNA
autoimmune single stranded DNA
avian myoblastosis virus, p19^(gag)
AVP
axonal filaments, 56 & 58 kDa (amphibian)
axons, CNS (Drosophila)
B lymphoid tyrosine kinase (Tyrosine-protein kinase Blk)
BACH1
BACH2; BTB and CNC homology 1, basic leucine zipper transcription factor 2
Baculoviral IAP repeat containing 3
Baculoviral IAP repeat containing 7
basement membrane marker
Basic helix-loop-helix family, member a9
Basic leucine zipper transcription factor ATF-like 3
Basic leucine zipper transcription factor, ATF-like 2
Basic leucine zipper transcription factor, ATF-like 3
BATF; Basic leucine zipper transcription factor, ATF-like
B-cell CLL/lymphoma 6
B-cell CLL/lymphoma 6; B-cell lymphoma 6 protein
B-cell lymphoma/leukemia 11A
BCL2 like 1
BCL2-like 2
BEAF
Beta Catenin like protein 1
beta-defensin 3
beta-galactosidase
BHK cells overexpressing mouse Glucagon-like peptide 1 receptor
Bicaudal-D
blastema, regenerating
blastemal regeneration cell marker of the newt
BMI1 polycomb ring finger oncogene; Polycomb complex protein BMI-1
BMX non-receptor tyrosine kinase
Bobby sox homolog
bodywall muscle cells
BolA family member 3
BolA-like protein 2
bone sialoprotein II
Botrytis cinerea
brain-derived neurotrophic factor, fish & human
brain-derived neurotrophic factor, mouse
BRCA1 Interacting Protein C-Terminal Helicase 1 Peptide 1
BRD1; Bromodomain containing 1
Breast cancer 1, early onset
Breast Cancer 1, Early Onset Peptide 1
Breast cancer type 1 susceptibility protein
Broad (core)
Broad (Z1)
Broad (Z3)
Bromodomain and PHD finger containing, 1
Bromodomain and WD repeat domain containing 1
Bromodomain containing 1
Bromodomain containing 3
Bromodomain containing 9
Bromodomain, testis-specific
Bruchpilot
Bruton agammaglobulinemia tyrosine kinase
BSX; Brain-specific homeobox
BTB and CNC homology 1, basic leucine zipper transcription factor 2
BTN1A1
BUB3-interacting and GLEBS motif-containing protein ZNF207
cactus
cadherin, B-
cadherin, C-
cadherin, DE-
cadherin, DN-
Cadherin, E-
cadherin, E- (canine)
cadherin, N-
cadherin, R-
cadherin-6B
cadherin-7
cadherin-8
calbindin-32, drosophila
Calcineurin B homologous protein 2 (Hepatocellular carcinoma-associated antigen 520)
calcium/calmodulin-dependent protein kinase kinase 2, beta
Calcyclin (Prolactin Receptor Associated Protein)
calmodulin
Calnexin
Calreticulin Peptide 1
calreticulin, recombinant Dictyostelium
CAMP responsive element binding protein 1
cAMP responsive element binding protein 5
CAMP responsive element binding protein-like 2
cAMP-specific phosphodieserase PDE4A4
cAMP-specific phosphodieserase PDE4A8
cAMP-specific phosphodieserase PDE4D5
Campylobacter rectus
Cap32/34
capping protein alpha-1 & alpha-2 subunits
capping protein beta-1 subunit
capping protein beta-2 subunit
carbohydrate epitope, probably globoseries
Carbonic anhydrase VIII
cardioactive peptide B
CARO2
Casein kinase I isoform epsilon
Casein kinase II subunit alpha
Casein kinase II subunit alpha prime
CASP8AP2; CASP8-associated protein 2
Caspase 8 associated protein 2
catenin, alpha- (Drosophila)
catenin, alpha N
catenin, beta-
catenin, p120
Caudal type homeobox 2
caveolin
CBFB; Core-binding factor subunit beta
Cbl proto-oncogene, E3 ubiquitin protein ligase
Cbl-L protein exon 6 (aa 449-878 of L isoform)
CBX2; Chromobox protein homolog 2
CCAAT/enhancer binding protein (C/EBP), beta
CD1
CD11a (LFA-1 alpha subunit)
CD11a (LFA-1 alpha subunit) (human)
CD11a (LFA-1 alpha subunit), murine
CD11b (Mac-1 alpha subunit), murine
CD11b (Mac-1), murine
CD11b (Mac-1, CR3) (human)
CD133/ Prominin-1
CD18 (beta subunit of CD11, a, b, c), murine
CD18 (beta subunit of CD11a, b, c)
CD2 (LFA-2)
CD21
Cd248
CD31 (PECAM-1)
CD44
CD44 (CRIII)
CD44 human, hyaluronate receptor
CD44 molecule (Indian blood group) Peptide 1
CD45 (lymphocyte common antigen) (human)
CD48
CD58 (LFA-3)
CD63 (human) LAMP
CD64
CD9
CDC5L; Cell division cycle 5-like
Cdk7, recombinant
CEBPE; CCAAT/enhancer binding protein (C/EBP), epsilon
CEBPZ; CCAAT/enhancer binding protein (C/EBP), zeta
Cell cycle and apoptosis regulator 2
Cell division cycle 34
Cell division cycle 34 homolog (S. Cerevisiae)
cell-junction marker
Centrosomal protein 170kDa
chaoptin
Checkpoint kinase 2
chemokine (C-X-C motif) ligand 9
chicken cell marker
Chloride channel calcium activated 3A1; CLCA1 protein
Chloride Intracellular Channel 1
choline acetyltransferase
Choline Kinase Alpha
chondroitin sulfate proteoglycans (carbohydrate epitope)
Chorionic Gonadotropin, beta polypeptide Peptide 1
Chromobox homolog 1
Chromobox homolog 3
Chromobox homolog 5
Chromogranin A
chromosome 1, 55-73 kDa polypeptides
chromosome 11, 40 and 80 kDa polypeptides
chromosome 12, 21 kDa product
chromosome 19, OKa blood antigen / CD147
Citron Rho-interacting kinase
Cleavage stimulation factor subunit 2
Cleavage stimulation factor subunit 2 tau variant
Clec4f
c-MYC
CNS, leech
CNS-specific antigen
Coactosin p17
Coiled-coil and C2 domain containing 1A
collagen (pro-) type I (aminopropeptide)
collagen type II
collagen type III
collagen type IV
collagen type IX
collagen type VI
collagen type X
collagen type XII
collagen type XVIII
collagen(pro-) type I
collagenase
Connectin C1.427
connexin 32
COPS3; COP9 signalosome subunit 3
Coracle
Core-binding factor subunit beta
Core-binding factor, beta subunit
coronin
Coronin N-terminal
Cortexillin I
Cortexillin II
Costal-2 (Cos2)
creatine kinase
Creatine kinase B chain
CREB3L4; CAMP responsive element binding protein 3-like 4
CrebA transcription factor
CREBL2; cAMP responsive element binding protein-like 2
Crumbs Drosophila protein
crystal protein
Crystallin Alpha B
csA (contact site A glycoprotein)
Csp
CSP2 chemosensory protein
CTBP1; C-terminal binding protein 1
C-terminal binding protein 1
C-terminal binding protein 2
Cubitus interruptus (Ci) full length
CUGBP, Elav-like family member 2
CUGBP, Elav-like family member 4
Cut homeobox
Cutoff protein, CG13190, full length protein
CXXC1; CXXC finger protein 1
Cyclic AMP-dependent transcription factor ATF-2
cyclic nucleotide-gated channel (rOCN2, rat)
Cyclin A
cyclin B
Cyclin D binding myb-like Transcription Factors 1
cyp-33E1, recombinant
Cystatin A
Cystatin B
cysteine string protein (CSP), Drosophila
cytokeratin type II (Xenopus)
D4, zinc and double PHD fingers family 1
Dacapo
Dachshund protein, Drosophila
Dally-like protein (Dlp)
DAO5
DAXX; Death-domain associated protein
DAXX; death-domain associated protein
DBX2; Developing brain homeobox 2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
Death-domain associated protein
Decapping mRNA 2
decorin
Deformed epidermal autoregulatory factor 1 homolog
Del-1
Deleted in liver cancer 1
Delta, extracellular domain
desmin
dFMR1
dFMRP
DGCR8 microprocessor complex subunit
DHPR alpha-subunit, skeletal muscle
DHPR beta subunit, skeletal muscle
Dip2
dipeptidylpeptidase IV
Disabled protein
Discoidin I (cAMP binding domain)
discs large (C. elegans)
Discs large (Drosophila)
Discs, large homolog 1 (drosophila)
Discs, large homolog 2 (drosophila)
Disp2 peptide (aa731-750 coupled to KLH)
DLAR
DLX3; Distal-less homeobox 3
DMPK
DNA (cytosine-5-)-methyltransferase 3 alpha
DNA (cytosine-5-)-methyltransferase 3-like
DNA ligase 3
DNA nucleotidylexotransferase
DNA repair protein XRCC1
DNA-binding protein Ikaros
DNA-binding protein inhibitor ID-1
DNA-binding protein inhibitor ID-3
DNA-binding protein RFX2
DNA-binding protein RFX5
DNA-binding protein RFX6
DNA-damage inducible transcript 3
DNA-damage-inducible transcript 3
Dorsal root ganglia homeobox
Dorsal, embryonic polarity protein
Doublesex and mab-3 related transcription factor 2
Doublesex- and mab-3-related transcription factor B1
Doublesex protein DNA binding domain (DBD)
DR1; down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DR1-associated corepressor
DR1-associated protein 1 (negative cofactor 2 alpha)
Draper
Dual specificity phosphatase 7
duct, exocrine gland
DVL2; Dishevelled segment polarity protein 2
DVL3; Dishevelled segment polarity protein 3
DYN-1
Dynein heavy chain
Dystroglycan, alpha
dystroglycan, alpha-
dystroglycan, beta-
dystrophin
dystrophin aa 71-74
dystrophin amino acids 1749-2248
dystrophin amino acids 816-1749
dystrophin amino-acids 1749-2248
dystrophin amino-acids 1749-2248 as TrpE fusion protein
dystrophin amino-acids 816-1749
dystrophin fragment encoded by exons 4-16
dystrophin fragment exons 45-50 aa 2145-2439
dystrophin fragment exons 70-79
E2F transcription factor 8
E3 ubiquitin-protein liase RNF8
E3 ubiquitin-protein ligase NEDD4-like
E3 ubiquitin-protein ligase RING2
E3 ubiquitin-protein ligase SMURF1
E4F transcription factor 1
Early B-cell factor 1
ecdysone receptor (EcR common)
ecdysone receptor (EcR) (common), Manduca sexta
ecdysone receptor (EcR) B1-isoform specific, Manduca sexta
ecdysone receptor (EcR-A)
ecdysone receptor (EcR-B1)
EDF1; Endothelial differentiation-related factor 1
EEA1; Early endosome antigen 1
Eef1b2
Efemp2
egg shell marker for C. elegans embryos
EHMT2; Euchromatic histone-lysine N-methyltransferase 2
elav Drosophila protein
elav Drosophila protein; embryonic lethal abnormal vision
ELF2; E74-like factor 2 (ets domain transcription factor)
ELF3; E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ELK1, member of ETS oncogene family
Embryonal carcinoma cell surface carbohydrate
Emerin (amino acids 11-17)
Emerin (amino acids 112-115 and 150-158)
Emerin (amino acids 112-115)
Emerin (amino acids 152-159)
Emerin (amino acids 221-228)
Emerin (amino acids 69-77)
Emerin (amino acids 7-15)
Emerin (amino acids 89-96)
Enabled
endoglin
endoglin (CD105)
endoplasmic reticulum, rough, glycoprotein
Engrail-1
Engrailed/invected gene products
Enolase superfamily member 1, Mitochondrial
Enoyl CoA hydratase, short chain, 1, mitochondrial
ENS-1; Embryonic Normal Stem Cell
entactin (synaptic)
EP300
EpCAM (murine)
EPH receptor B4
EphB1, EphB2, EphB3
ephrin-B1
epidermal growth factor receptor
epithelial stem cell marker
epithelial surface marker, apical
EPS15, Drosophila
ER81
ERM-1, amino acids 209-563
ESRRA; Estrogen-related receptor alpha
ESRRG; Estrogen-related receptor gamma
estrogen receptor alpha, ligand binding domain (aa 304-554)
Estrogen Receptor Binding Site Associated, Antigen 9
Estrogen-related receptor beta; Steroid hormone receptor ERR2
ETC-related transcription factor ELF-1
Ets variant 6
Ets variant 7
ETV7; Ets variant 7
Eukaryotic elongation factor-2 kinase
Eukaryotic translation initiation factor 2, subunit 1 alpha
Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
Eukaryotic translation initiation factor 4A3
Eukaryotic translation initiation factor 4E
Even-skipped protein
Even-skipped protein (Drosophila)
Evx1
Exosome complex exonuclease RRP44
Extra Sex Combs (ESC)
Extradenticle protein (EXDHDcc)
Eyeless protein, linker region
Eyes Absent (Eya) protein
Ezrin (p81)
Fas (TNFRSF6) associated factor 1
fasciclin I (Drosophila)
fasciclin I (grasshopper)
fasciclin II (Drosophila)
fasciclin II (Drosophila, all isoforms)
fasciclin II (grasshopper)
fasciclin II (Manduca sexta)
Fasciclin III (Drosophila)
Fascin
Fatty acid synthase
Fatty acid-binding protein, epidermal
Fatty acid-binding protein, intestinal
FBJ murine osteosarcoma viral oncogene homolog B
Fbln2
Feline Gardner-Rasheed sarcoma viral oncogene homolog
female lethal (2)D
Fer tyrosine kinase
FEZ family zinc finger 2
fibrillin 2-like
fibrinogen
fibronectin
fibronectin (III-14 in Hep2)
fibronectin (III-15)
fibronectin, cell binding domain
filament antigen
Fimbrin
Fimbrin (p67)
Flamingo
FLI1; Fli-1 proto-oncogene, ETS transcription factor
floor plate marker
fluorescein isothiocyanate-conjugated to keyhold limpet hemocyanin
Fly Bag-of-marbles
FMR1
FMRP
Forkhead box A3; Hepatocyte nuclear factor 3-gamma
Forkhead box B2
Forkhead box D3
Forkhead box I1
Forkhead box J2
Forkhead box N1
Forkhead box P4
Forkhead box protein P3
Forkhead box protein P4
FosB; FBJ murine osteosarcoma viral oncogene homolog B
FOS-like antigen 2
Fos-related antigen 1
FOXI1; Forkhead box I1
FOXL1; Forkhead box L1
FOXM1; Forkhead box M1
FOXO3; Forkhead box O3
FOXR1; Forkhead box R1
Frizzled protein
Frizzled2
Fstl3
Fukutin
Fumarate hydratase, mitochondrial
Fused (Fu)
Fused in sarcomas/RNA-binding protein FUS
futsch
FXR2
G protein-coupled receptor kinase 5
GA binding protein transcription factor, beta subunit 1
GA-binding protein alpha chain
ganglioside GD1a
ganglioside GD1b
ganglioside GM1
Ganglioside GT1b
GASP (Gene Analogous to Small Peritrophins)
GATA4; GATA binding protein 4
GBX-1 homeobox protein
GBX1; Gastrulation brain homeobox 1
GD2 glycolipid
Gelsolin
gemin4
gemin5
gemin6
Geminin
General transcription factor IIF subunit 2
General transcription factor IIH subunit 2
General transcription factor II-I repeat domain-containing protein 2A
General transcription factors IIi
germ cells, male, rodent
germ-line-specific P granules
gigas gene product
Glass bottom boat; Protein 60A
glass Drosophila protein
GLI family zinc finger 1
Glial cells missing homolog 2
glial precursor
Glorund
Glucagon-like peptide 1 receptor
Glucocorticoid modulatory element-binding protein 2
Glucose phosphate isomerase
Glutamate receptor interacting protein 1
Glutamate receptor subunit, DGluR-IIA
Glutamate-Cysteine Ligase Regulatory Subunit
Glutamic acid decarboxylase; GAD
Glutamic-oxaloacetic transaminase 2, mitochondrial
Glutathione S Transferase Mu3
Glutathione S-Transferase Mu1
Glutathione S-Transferase Mu2
Glutathione S-Transferase Pi 1 Peptide 1
glutathione-S-transferase
Glyceraldehyde-3-phosphate dehydrogenase (hGAPDH)
glycolipid; epitope is an alpha-galactose lactoseries carbohydrate
glycoprotein, Cladosporium herbarum race 4
glycoprotein, Ulocladium
glyoxylate cycle protein
GOBP1 olfactory binding protein
GOBP2 olfactory binding protein
Golgi microtubule-associated protein
Golgin-245 ortholog
gp135/podocalyxin
gp210
GPIb; von Willebrand factor receptor; GPIb/IX complex
Grainyhead-like 1
Grainyhead-like 1 homolog
Grainyhead-like protein 1
GRAM domain containing 4
Green fluorescent protein (GFP)
Green fluorescent protein (GFP) variant
Groucho protein
Growth Factor Receptor-Bound Protein 2 Peptide 1
Growth factor receptor-bound protein 7
GST fused to a fragment of the Klarsicht alpha protein (amino acids 1895-2262) from Drosophila melanogaster
GST fused to a fragment of the Klarsicht alpha protein (amino acids 277-556) from Drosophila melanogaster
GST fused to a fragment of the Klarsicht alpha protein (amino acids 875-1169) from Drosophila melanogaster
GTF2F2; General transcription factor IIF, polypeptide 2, 30kDa
GTF2H2 family member C
Guanine nucleotide binding protein (G protein), gamma 2
Gurken protein
H6 family homeobox 3
Hairy/ enhancer-of-split related with YRPW notif protein
Hairy/ enhancer-of-split related with YRPW notif protein 2
Half pint protein, C-terminal half (amino acids 277-637)
HAND2; Heart and neural crest derivatives expressed 2
HCP4
HCS-1 (Hair Cell Soma-1) / otoferlin
Headcase protein (amino acids 1-417)
Heart and neural crest derivatives expressed 1
Heat shock 22kDa protein 8
Heat shock 27kDa protein 1
Heat Shock 27kDa Protein 1 Peptide 1
Heat Shock 27kDa Protein 1 Peptide 3
Heat shock 60kDa protein 1 (chaperonin)
Heat Shock Protein-100
Heat shock transcription factor 2
Heat shock transcription factors 2
hemapoietic stem cell protein, 74 kDa
Hematopoietic SH2 domain containing
hemocytes, moth larvae
heparan sulfate proteoglycan
heparan sulfate proteoglycan (basement membrane)
Hepatocyte nuclear factor 3-beta
Hepatocyte nuclear factor 4, alpha
Hepatoma derived growth factor-like 1
Hepatoma-derived growth factor
Hepatoma-derived growth factor-related protein 2
HES1; Hes family bHLH transcription factor 1
HES3; Hes family bHLH transcription factor 3
HESX1; HESX homeobox 1
Heterochromatin Protein 1
hevin (SC1, SPARC-like 1)
hexokinase (Type I isozyme)
HHEX; Hematopoietically expressed homeobox
HIF3A; Hypoxia inducible factor 3, alpha subunit
High mobility group 20A
High mobility group box 1
highwire
hindsight: zinc-finger nuclear protein hindsight;
Hisactophilin, Dd gelation factor
histone 2A variant (gamma-H2AV) peptide phosphorylated (QDPQRKGNVILSQAY)
Histone chaperone Anti-silencing function 1B
Histone deacetylase 7
Histone deacetylase 8
Histone H4 Transcription Factors
Histone lysine demethylase PHF8; PHD finger protein 8
Histone-arginine methyltransferase CARM1
Histone-lysine N-methyltransferase EZH2
Histone-lysine N-methyltransferase NSD2
Histone-lysine N-methyltransferase SETD7
Histone-lysine N-methyltransferase SMYD3
HLF; Hepatic leukemia factor
HLFA, beta-subunit
HMGA1; High mobility group AT-hook 1
HMGA1; High mobility group AT-hook 1
HMGB1; High mobility group box 1
HMGXB4; HMG box domain containing 4
HMR-1, amino acids 1099-1223
HNF3b / FoxA2
HNK-1 epitope
Homeobox and leucine zipper encoding
Homeobox and leucine zipper protein Homez
Homeobox B2; HOXB2
Homeobox B6
Homeobox C8
Homeobox protein HMX3
Homeobox protein Hox- B5
Homeobox protein Meis 2
Homeobox protein Meis 3
Homeobox protein Nkx-2.5
Homeobox protein Nkx-3.2
Homeobox protein Nkx-6.1; Nkx6.1
Homeobox protein PKNOX2
Homeodomain-only protein
HOP homeobox
Hoxb4
Hoxc10
Hoxc9
HOXD9; Homeobox D9
HSF1; Heat shock transcription factor 1
HSF5; Heat shock transcription factor family member 5
HSP-60, amino acids 1-547
htsRC
huntingtin
Hydroxysteroid (17-beta) dehydrogenase 10
hypodermal marker
hypodermis (seam cells)
Ia antigen (chicken)
Ia antigen (quail)
ICAM-1
ID2; Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3; Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4; Inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
ID4; Inhibitor of DNA binding 4, dominant negative HLH protein
IL2-inducible T-cell tyrosine-protein kinase
InaD-like protein
Indoleamine-pyrrole 2,3 dioxygenase
Inhibitor of growth family, member 1
Inhibitor of growth family, member 4
INSM1; Insulinoma-associated 1
insulin (pro-) non-processed
insulin (proinsulin; C-peptide)
Insulin gene enhancer protein ISL-1
Insulin-like growth factor binding protein 2
integrin alpha 2 (CD49b, VLA2, ITGA2, ECMR II)
integrin alpha V subunit (CD51, fibronectin receptor alpha subunit)
integrin alpha V/5 + beta 5 (CD49e, CD51, fibronectin/vitronectin receptor)
integrin alpha-2
integrin alpha-2 (CD49b)
integrin alpha-2; alpha2beta1 integrin complex
integrin alpha-2b beta-3
integrin alpha-3
integrin alpha-3 (CD49c)
integrin alpha-4 (CD49d)
integrin alpha-5
integrin alpha-5 (avian)
integrin alpha-5 (CD49e)
integrin alpha-6
integrin alpha-6 (avian)
integrin alpha-7 (avian)
integrin alphaPS1 (multiple edematous wing)
integrin alphaPS2 (inflated)
integrin beta
integrin beta 3 (amino acids 26-40)
integrin beta-1
integrin beta-1 (avian)
integrin beta-1 (CD29)
integrin beta-1 (Xenopus)
integrin beta-2 (CD18)
integrin beta-3
integrin betaPS (myospheroid)
integrin, alpha-V beta-5 heterodimer
Integrin, beta-1 subunit
Integrin-linked protein kinase
intercostal nerves
intercostal nerves in a rostrocaudal gradient
Interferon regulatory factor 3
Interferon regulatory factor 8
Interferon-inducible double stranded RNA dependent protein kinase activator A
Interleukin 18
Interleukin 18 Peptide 1
Interleukin 6
intermediate filament subunit
Intestine-specific
Intraflagellar transport protein p139
Intraflagellar transport protein p172
Intraflagellar transport protein p57/55
Intraflagellar transport protein p81
IRF2; Interferon regulatory factor 2
IRF3; Interferon regulatory factor 3
Iroquois-class homeodomain protein IRX-5IRX5
ISL1; ISL LIM homeobox 1
Islet delta cells
Islet-1 homeobox
Islet-1 Islet-2 homeobox
Islet-1 specific homeobox
Islet-2
itchy homolog E3 ubiquitin protein ligase
Jade -1 protein
Jagged1 (JAG1)
JAZF zinc finger 1
JAZF zinc finger 1; JAZF1
JAZF1; JAZF zinc finger 1
Junctions, epidermal cell:cell
JUP; Junction plakoglobin
KDM1A; Lysine (K)-specific demethylase 1A
KDM8; Lysine (K)-specific demethylase 8
kel 1B
Kelch Domain Containing 8A Peptide 1
keratan sulfate
keratan sulfate (brain)
keratin type I
Keratin, type I cytoskeletal 19
Keratin, type II cytoskeletal 8; Cytokeratin endoA
keratinocyte, basal, cell attachment antigen (human)
KH domain containing, RNA binding, signal transduction associated 1
KH domain containing, RNA binding, signal transduction associated 3
KI-67; Marker of proliferation Ki-67
KIAA1967
kinesin
Kinesin family member 13B
Kinesin-like protein KIF2C
Kinetochore protein NDC80 homolog
KLF10; Kruppel-like factor 10
KLF10; Kruppel-like factor 10
KLF15; Kruppel-like factor 15
KLF16; Kruppel-like factor 16
KLOTHO
Krueppel-like factor 15
Kruppel-like factor 1 (erythroid)
Kruppel-like factor 10
Kruppel-like factor 14
Kruppel-like factor 17
Kruppel-like factor 5 (intestinal)
Kruppel-like factor 7
L1 protein (rat)
L1CAM and NCAM
L1-like CAM (avian)
L3MBTL4; L(3)mbt-like 4 (Drosophila)
lactadherin
lactase-phlorizin hydrolase
Lactoylglutathione lyase
lacunin
lamin
lamin A/C (recombinant)
lamin C
lamin Dm0
laminin
laminin 5 (epiligrin, LAMA3, laminin-5 alpha subunit)
laminin B2
laminin, gamma-1 chain
laminin, S-
laminin/fibronectin receptor
laminin-binding lectin
LAMP (gene symbol: Lsamp)
LAMP-1
LAMP-1 (CHO)
LAMP1; Lysosome-associated membrane glycoprotein 1
LAMP-2
LAMP-2 (110 kDa lysosomal membrane glycoprotein)
LAMP-2 (CHO)
LAMP-2 (human)
late bloomer
L-CAM, E-cadherin, uvomorulin
LCOR; Ligand-dependent nuclear receptor corepressor
LET-413 (amino acids 460-606)
Lethal(3)malignant brain tumor-like protein 4
Leucine aminopeptidase
Leucine rich repeat (in FLII) interacting protein 1
leukocyte, activated, cell surface glycoprotein
LEUTX; Leucine twenty homeobox
Ligand-dependent nuclear receptor corepressor-like
Lim 1+2 / LhxV5
LIM domain binding 1
LIM homeobox 2; LHX2
LIM homeobox 4
LIM/homeobox protein Lhx2
Lim3
LIN-28 homolog A
Lin-7 homolog C
link protein
lipooligosaccharide (LOS)
LMP-1, amino acids 18-160
LMX
L-myc protein
lost protein, recombinant, expressed in E. coli
lozenge
Lymphoid-specific helicase,
Lysine (K)-specific demethylase 2A
Lysine (K)-specific demethylase 4A
Lysine (K)-specific demethylase 4C
Lysine (K)-specific demethylase 4E
Lysine (K)-specific demethylase 6B
lysine decarboxylase (E. corrodens)
Lysine(K)-specific demethylase 6B
Lysine-specific demethylase 2A
lysosomal membrane glycoprotein (formerly called cv24)
lysosomal membrane glycoprotein (LEP-100) / CD107
Lysosomal-associated membrane protein 1; Lamp-1 ; CD107a
M2, membrane protein
M6, membrane protein
MAFB; V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAFF; V-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG transcription factor
major sperm protein (MSP)
Malate dehydrogenase 1 NAD (soluble)
Malate dehydrogenase 2, NAD (mitochondrial)
maltase-glucoamylase
Maltose binding protein
mannose 6-phosphate / IGF II receptor, cation-independent
mannose 6-phosphate receptor, cation-dependent
MAT2B; Methionine adenosyltransferase II, beta
Math1 (Atoh1)
MAX; MYC associated factor X
MAX-like protein X
MAZ; MYC-associated zinc finger protein (purine-binding transcription factor)
MBNL1 (muscleblind-like splicing regulator 1)
MBNL2 protein (muscleblind-like splicing regulator 2)
MBNL3 protein (muscleblind-like splicing regulator 3)
MBP-sigma 1s
MBP-sigma NS-His
mCherry fluorescent protein
MED4; Mediator complex subunit 4
Mediator complex subunit 1
Mediator of DNA-damage checkpoint 1
Megakaryocyte-associated tyrosine kinase
Meis homeobox 2
Meis homeobox 3
MEIS2; Meis homeobox 2
melanoblasts and melanocytes of neural crest origin (avian) / glutathione S-transferase (alpha subunit)
Melanoma Antigen Family A, 4
Menin
Mesoderm posterior 1 homolog
mesoderm, early, rodent
Metastasin 100 calcium-binding protein A4 (Calvasculin)
Methyl CpG Binding Protein 1
Methyl-CpG binding domain protein 4
METTL21A; Methyltransferase like 21A
MHC class I
MHC class II
Microcephalin
microfibrils (sea urchin)
mineralocorticoid receptor
Mitogen-activated protein kinase 1
Mitogen-activated protein kinase 14
Mitogen-activated protein kinase 8
Mitogen-activated protein kinase kinase kinase 7
Mitotic spindle assembly checkpoint protein MAD2A
MLLT10; Protein AF-10
MLLT3; AF-9
MLX interacting protein
Mmp1 catalytic domain
Mmp1 hemopexin domain
MNR2/HB9/Mnx1
Moesin
Mortality factor 4-like 1
Mothers against decapentaplegic homolog 1
Mothers against decapentaplegic homolog 4
mouse Rb, last 200 amino acids (GST-Rb)
MSH3 aa 24-308
MSX1+2
MUC17 CRD1 L CRD2
Mucin 1, cell surface associated Peptide 1
Mucin 1, cell surface associated Peptide 2
Multiple endocrine neoplasia I
Muscle
muscle fast C-protein
muscle marker
muscle slow C-protein
muscle/neurite marker
Muscleblind-like splicing regulator 3
Mutanase G
MYC induced nuclear antigen
MYCN; N-myc proto-oncogene protein
Myeloid zinc finger 1
MYO1B; Myosin IB
myoblast marker (avian)
myoblast, chondrocyte marker (avian)
myoblast, fibroblast marker (avian)
Myocyte enhancer factor 2A
Myocyte enhancer factor 2B
Myocyte enhancer factor 2C
MyoD
Myogenin
myomesin
myosin (embryonic)
myosin (human neonatal slow and fast IIa fibers)
Myosin all isoforms
myosin fast muscle light chain 2
myosin heavy chain
Myosin heavy chain (all but 2X)
Myosin heavy chain (all fast isoforms)
Myosin heavy chain (human fast fibers)
Myosin heavy chain (human nascent secondary and all fast fibers)
Myosin heavy chain (human neonatal and adult fast fibers)
Myosin heavy chain (human neonatal fast IIa fibers)
Myosin heavy chain (human slow fibers)
Myosin heavy chain (slow and 2A)
Myosin heavy chain (slow, alpha- and beta-)
myosin heavy chain A
Myosin Heavy Chain Type I
Myosin Heavy Chain Type IIA
Myosin Heavy Chain Type IIB
myosin heavy chain, adult
myosin heavy chain, avian fast isoforms and rat, rabbit isoforms including type IIb fibers
myosin heavy chain, avian fast isoforms and rat, rabbit, and turtle isoforms
myosin heavy chain, avian fast isoforms and rat, turtle, newt, frog, fish, ray, and shark isoforms
myosin heavy chain, avian slow isoforms; reacts with isoforms of other species
myosin heavy chain, avian slow myosin and mammalian isoforms
myosin heavy chain, avian slow myosin heavy chain 1, 2 and 3
myosin heavy chain, avian slow myosin heavy chain 2 and 3; slow muscle fibers in zebrafish
myosin heavy chain, embryonic
myosin heavy chain, embryonic and adult fast
myosin heavy chain, embryonic and neonatal fast
myosin heavy chain, fast, 2A
myosin heavy chain, fast, 2B
Myosin heavy chain, fast, 2X
myosin heavy chain, fast, extraocular specific
myosin heavy chain, fast, jaw muscle specific
myosin heavy chain, multiple avian and rat, rabbit, turtle, newt and fish isoforms
myosin heavy chain, neonatal and adult
myosin heavy chain, neonatal fast
myosin heavy chain, sarcomere
myosin heavy chain, slow, SM1 only
myosin heavy chain, slow, SM2
myosin heavy chain, slow, SM2 only
myosin heavy chain, SM2 and atrial
myosin heavy chain, ventricular
myosin II
myosin II heavy chain
myosin IIB, cytoplasmic non-muscle
myosin light chain 1 and 3f (LC1f/3f)
myosin light chain 1s (LC1s)
myosin light chain 1s, 2s, 1f and 2f (LC1s, LC1f, LC2s, LC2f)
myosin, sarcomere (MHC)
myosin-VIIa
myotactin
myotendinous antigen (tenascin)
MZF1; Myeloid zinc finger 1
Na-K-Cl cotransporter
Na-K-Cl cotransporters (shark)
NAPA-73 (neurofilament-associated protein, 73 kDa)
NCAM
NCAM (cytoplasmic domain)
NCAM (extracellular domain)
NCAM (sialylated form); PSA-NCAM
NCAM/L1CAM leech homologue
NCK adaptor protein 1
NCOA1; Nuclear receptor coactivator 1
NEDD8-conjugating enzyme Ubc12
Nervana protein
nervous system
Nestin (intermediate filament protein)
Nestin/radial glial marker
neural associated ganglioside
neural crest cells
neural marker
neural precursor cell expressed, developmentally down-regulated 4 isoform 1
neural precursor cells
neural retinal gangliosides (9-0-acetyl-GD3)
neural specific
neural tube, dorsal
neurocan (C-terminal epitope)
neurocan (N-terminal epitope)
neurocan receptor
neurofilament (160 kDa)
Neurofilament (165 kDa)
Neurofilament associated
neurofilaments
neurofilaments, primary sensory and motor
neurogenin 3
neuroglian (Drosophila, neuron-specific)
neuroglian (Manduca sexta)
Neuromedin-B peptide
neuromuscular junction and reactive Schwann cell associated antigen
neuron (motor) antigen
neuronal cell surface marker
neuronal cell surface marker (SC-1, DM-GRASP, BEN)
neuronal marker (cytoplasmic)
neuronal marker (TAG-1)
neuronal, mesencephalic trigeminal cell surface marker
neuronal, motor, marker (SC-1)
Neurons, cephalic ganglia and ventral cord
neurons, cytoplasmic
neuropil region and primary motor neuron axons
Neuropilin-1
neurotactin (Drosophila)
NFATc1
NFATc2
NFE2L2; Nuclear factor, erythroid 2-like 2
NFKB1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFYB; Nuclear transcription factor Y, beta
NFYC; Nuclear transcription factor Y, subunit gamma
NHE3, cation proton antiporter 3
nicotinic receptor, neuronal
nidogen/entactin
NINJ2; Ninjurin 2
Nkx2.2 transcription factor
NKX2-5; NK2 homeobox 5
NKX3-1; NK3 homeobox 1
Nkx6.1
N-lysine methyltransferase SETD6
N-lysine methyltransferase SMYD2
N-myc (and STAT) interactor
N-myc proto-oncogene protein
NO66; Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66
Non-histone chrmosomal protein HMG-14.
Non-histone chromosomal protein HMG-14
Norovirus RNA-dependent RNA polymerase
Notch, extracellular domain, EGF repeats #12-20
Notch, extracellular domain, EGF repeats #5-7
Notch, intracellular domain
Notch1
Notch2
notochord and neuropil
notochord marker
Nov
NR5A1; Nuclear receptor subfamily 5, group A, member 1
NrCAM
NRF1; Nuclear respiratory factor 1
Nuclear factor 1 A-type
Nuclear factor I A-type
Nuclear factor of activated T-cells, cytoplasmic 3
Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 2 Peptide 1
Nuclear factor, interleukin 3 regulated
nuclear lamins II/III (Xenopus)
nuclear membrane marker
Nuclear receptor co-repressor 1
Nuclear receptor subfamily 0, group B, member 1
Nuclear receptor subfamily 1, group D, member 1
Nuclear receptor subfamily 1, group D, member 2
Nuclear receptor subfamily 2, group C, member 1
Nuclear receptor subfamily 5, group A, member 2
Nuclear respiratory factor 1
nucleolar protein
nucleolin (95 kDa and 90 kDa isoforms)
nucleolin (95 kDa isoform)
nucleoplasmin
Nucleoplasmin-3
Nucleoside Diphosphate Kinase A (nm23-H1)
Nucleoside Diphosphate Kinase B
Nucleosome assembly protein 1-like 5
Nucleus accumbens-accociated protein 1
Nucleus accumbens-associated 1
Nucleus accumbens-associated protein 2
Nucleus, intestine and epidermis
nullo-GST fusion protein, an inframe of the entire nullo protein to c-terminus of GST
Numb
OBFC1; Oligonucleotide/oligosaccharide-binding fold containing 1
oligodendrocyte (myelin) marker (amphibian)
oligodendrocytes and their processes
oncomodulin (beta-parvalbumin)
One cut homeobox 2
ONECUT1; One cut homeobox 1
orb protein
orb2 protein
ORC-2
Origin recognition complex, subunit 1
Ornithine Decarboxylase 1
Orthodenticle homeobox 2
Osa
osteonectin
osteopontin
OTU domain, ubiquitin aldehyde binding 1
OTU domain, ubiquitin aldehyde binding 2
OTU domain-containing protein 6B
Otx1
outer membrane protein-19 (OMP-1g)
P granule
P granule + body muscle
P2X7
p46 cell surface protein excluded from macropinocytic cup
p53
P6 protein N-terminus Haemophilus influenzae
P6 surface antigen from Haemophilus influenzae
p80 endosomal membrane protein
P85A
PABA peptide hydrolase (meprin)
Paired box 5
Paired box 9
Paired related homeobox 2
PAR-3
paramyosin
Parvimonas micra
PAS-7
Patched
PAWR; PRKC apoptosis WT1 regulator
Pax3
Pax4 fusion protein (aa 132-171)
PAX5; Paired box 5
Pax6
Pax7
PAX-interacting protein 1
PBP2 olfactory binding protein
PBP3 olfactory binding protein
PBX4; Pre-B-cell leukemia homeobox 4
PBX4; Pre-B-cell leukemia homeobox 4
Pdx1
PDZ and LIM Domain 1
peanut gene protein product
PECAM
Peptide II B 80kD
Peregrin; Bromodomain and PHD finger containing, 1
Pericardin
Perilipin 2
perlecan
perlecan (domain IV)
Peroxiredoxin 2 Peptide 1
Peroxiredoxin 2 Peptide 2
Peroxiredoxin 4
Peroxiredoxin 4 Peptide 1
Peroxisome proliferator-activated receptor alpha
Peroxisome proliferator-activated receptor delta
PGBD1; PiggyBac transposable element derived 1
Pgp-1 (Ly-24) lymphocyte cell adhesion glycoprotein
pharyngeal marker
PHD finger protein 10
PHD finger protein 19
PHD finger protein 21B
PHD finger protein 7
PHD finger protein 8; Histone lysine demethylase PHF8
Phenylethanolamine N-methyltransferase
phosphacan/protein tyrosine phosphatase – z/b
Phosphatidylethanolamine Binding Protein 1
Phosphatidylinositol 3-kinase regulatory subunit alpha
phosphatidylinositol-specific phospholipase C
Phosphogluconate dehydrogenase
Phosphoglycerate dehydrogenase
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Phosphoinositide-3-kinase, regulatory subunit 2 (beta)
Phosphoserine Aminotransferase 1
Phosphoserine phosphatase-like
photoreceptors (rods and cones)
photoreceptors (rods only)
pigment cell marker (sea urchin)
Pigment dispersing factor (PDF) precursor-related peptide
Pigment-dispersing factor neuropeptide
PIKFYVE
PIKFYVE; Phosphoinositide kinase, FYVE finger containing
PLAG1; Pleiomorphic adenoma gene 1
plasmalemma vesicle-associated protein (PLVAP)
plateins (alpha-, beta- & gamma-)
plateins (beta- & gamma-)
PLXNB1; Plexin B1
Podoplanin
POLE3; Polymerase (DNA directed), epsilon 3, accessory subunit
Poly (ADP-ribose) polymerase 1
Poly (ADP-ribose) polymerase family, member 11
Polychaetoid
Polycomb group ring finger 3
Polycomb group ring finger 6
Polymerase (DNA directed), lambda
Polymerase (DNA directed), mu
Pop1 (BVES)
porin
Porphyromonas gingivalis
Porphyromonas gingivalis (cell surface antigen)
Posterior sex combs protein
Potassium channel modulatory factor 1
POU class 5, homeobox 1
POU class 6 homeobox 1
POU3F2; POU class 3 homeobox 2
POU5F1; POU class 5 homeobox 1
PPARD; Peroxisome proliferator-activated receptor delta
PPP1R10; Protein phosphatase 1, regulatory subunit 10
PPP1R10; Serine/threonine-protein phosphatase 1 regulatory subunit 10
PPP5C; Protein phosphatase 5, catalytic subunit
PR domain containing 7; PRDM7
PR domain zinc finger protein 1
PR domain zinc finger protein 13
PR domain zinc finger protein 4
PR domain zinc finger protein 8
PRDM16; PR domain containing 16
PRDM2; PR domain containing 2, with ZNF domain
PRDM7; PR domain containing 7
PRDM7; PR domain containing 7
PRDM8; PR domain zinc finger protein 8
Pre-B-cell leukemia homeobox 1
Prevotella intermedia (cell surface antigen)
Prevotella intermedia and nigrescens (cell surface antigen)
primordial germ cell surface marker (mouse)
PRMT7; Protein arginine methyltransferase 7
profilin
profilin II proteins
Proliferating Cell Nuclear Antigen Peptide 1
Prospero homeobox 1
Prospero protein
Proteasome subunit
Proteasome subunit 5
Protein arginine methyltransferase 6
Protein C-ets-1
Protein L-Myc
Protein Phosphatase 2A
Protein Smaug homolog 2
Protein tyrosine kinase 6
protein tyrosine phosphatase 69D
Protein tyrosine phosphatase, non-receptor type 1
protein tyrosine phosphatase, non-receptor type 6
protein tyrosine phosphatase, receptor-linked, DPTP10D
protein tyrosine phosphatase, receptor-linked, DPTP99A
proteoglycan, hyaluronic acid binding region; aggrecan
Proto-oncogene c-Fos
Proto-oncogene tyrosine-protein kinase Src
PRRX2; Paired related homeobox 2
PTP-ER
Pumilio homolog 1
puromycin
Putative histone-lysine N-methyltransferase PRDM6
Quail cell marker
Quail endothelial cell surface
RAC-gamma serine/threonine-protein kinase
RAD18 Homolog Peptide 1
RAD52 homolog (S. cerevisiae)
radial glial cells
radial glial cells / vimentin
Rarres2
Ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1)
RBBP5; Retinoblastoma binding protein 5
RCOR2; REST corepressor 2
RecD protein
Receptor-type tyrosine-protein phosphatase delta
Receptor-type tyrosine-protein phosphatase epsilon
Receptor-type tyrosine-protein phosphatase-like N
reelin
Reg1a
Reg3g
Regulation of nuclear pre-mRNA domain containing 1A
RelA-associated inhibitor
relaxin hormone
Relish
reovirus
reovirus capsid protein mu 1C
reovirus gamma 2 vertex protein
reovirus outer capsid protein sigma 3
reovirus sigma 1s
reovirus sigma NS
Repo; Reversed polarity protein
REST corepressor 3
Retina and anterior neural fold homeobox
Retinal homeobox protein Rx
retinal space (mechanoreceptors?)
Retinoic acid receptor RXR-gamma
Retinoic acid receptor, beta
Retinoid X receptor RXR- gamma
Retinoid X receptor, gamma
RFX5; DNA-binding protein RFX5
RFX6; Regulatory factor X, 6
RFXANK; Regulatory factor X-associated ankyrin-containing protein
RGCC; Regulator of cell cycle
RGS12 (“Regulator of G Protein Signaling-12”); N-terminal peptide PDZ & PTB domains
Rho guanine nucleotide exchange factor (GEF) 12
rho1
rhoB
rhodopsin 1 (Rh1 Drosophila)
Rhox homeobox family, member 2
Ribonucleotide Reductase M2 Peptide 1
Ribonucleotide Reductase M2 Peptide 2
ribosomal protein L3
Ribosomal protein S6 kinase alpha-5
ribosome, (E. coli)
ribosome, 30S (E. coli)
rim
RME-1, amino acids 333-575
RNA binding protein 8A
Rnase1
RNF113B; Ring finger protein 113B
RNF20; Ring finger protein 20, E3 ubiquitin protein ligase
Robo (Drosophila)
Robo1 (vertebrate)
Robo3 cytoplasmic (Drosophila)
Robo3 extracellular (Drosophila)
Rop
Ror2 (Nt 2535-2835)
RORA; RAR-related orphan receptor A
RORgt
rough Drosophila protein
Rumpelstiltskin
Runt-related transcription factor 2
RUVBL1; RuvB-like AAA ATPase 1
RXRA; Retinoid X receptor, alpha
ryanodine receptor, skeletal
ryanodine receptors
S100 calcium binding protein A2
SAC1
S-adenosylhomocysteine hydrolase
sarcalumenin
SATB1; SATB homeobox 1
SAX7, recombinant amino acids 1051-1144
scabrous Drosophila gene protein
SCAND3; SCAN domain containing 3
SCAR
Schwann cell & myoblast plasma membrane glycoprotein
Schwann cell marker, P(o) (avian)
Schwann cell myelin protein
Scm-like with four mbt domains 1
Scm-like with four MBT domains 2
SCRT1; Scratch family zinc finger 1
Secretory cell, peripharyngeal
selectin, E-
Selenoprotein P
Sema I (grasshopper)
Sema II
sensory cilia and excretory pore marker
Serine/threoinine-protein kianse Chk2
Serine/threonine-protein kinase Chk2; Checkpoint kinase 2
Serine/threonine-protein kinase D1
Serine/threonine-protein kinase OSR1
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin) Member 6 Peptide 1
Serpin Peptidase Inhibitor, Clade A, Member 1
Serrate, RNA effector molecule
SET nuclear proto-oncogene
Seven-up
Sex comb on midleg-like protein 4
Sex combs reduced homeotic protein
Sex determining region Y protein
sex-lethal protein
SH2 domain containing 1A; Duncan disease SH2- protein; SLAM-associated protein
SH2 domain containing 4A
SH2 domain-containing protein 1A
SH2 domain-containing protein 3A
SH2 domain-containing protein 4A
SH2B adaptor protein 2
SH3-domain binding protein 2
Sharpin
SHC (Src homology 2 domain containing) family, member 4
Shot
sialomucin complex (Muc4)
sidestep
Signal transducer and activator of transcription 1, 91kDa
Signal transducer and activator of transcription 1-alpha/beta
Signal transducer and activator of transcription 4
Signal transducer and activator of transcription 5A
Signal transducer and activator of transcription 5B
Sir2 (Drosophila)
SIRT2; Sirtuin 2
Sirtuin 1
Sirtuin 2
Sirtuin 5, mitochondrial
Sirtuin 5;
SIX homeobox 5
SIX5
skeletal muscle marker, 102 kDa
SKI-like protein
SLC25A24; Solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC30A9; Zinc transporter 9
SLC4A1, anion exchanger 1
slit protein, C-terminal
Slug
SMAD family member 3
SMAD family member 7
Smad nuclear-interacting protein 1
SMAD4; SMAD family member 4
Small ubiquitin-related modifier (SUMO)
SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SMARCE1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
SMN protein aa 159-209
SMN protein aa 159-209 Exon 4
SMN protein aa 210-241 Exon 5
SMN protein aa 28-91
SMN-interacting protein-1 (Gemin2)
Smoothened (Smo)
Snail family zinc finger 3
snRNA-activating protein complex subunit 4
SNW domain containing 1
Sodium/bile acid cotransporter
Solute Carrier Family 31 (Copper Transporter), Member 1 Peptide 1
Solute Carrier Family 31 (Copper Transporter), Member 2 Peptide 1
somatomedin-C; Sm-C/IGF-1
sonic hedgehog
SOX12; SRY (sex determining region Y)-box 12
SOX3; Transcription factor SOX-3
SOX4; (SRY sex determining region Y)-box 4
SOX4; SRY (sex determining region Y)-box 4
SP110 nuclear body protein
SP140 nuclear body protein
SPARC (osteonectin)
SPARC, recombinant human
Spectrin, alpha
Spermatogenesis and oogenesis specific basic helix-loop-helix 1
Spermidine or Spermine N1-Acetyltransferase 1
Spindle-F full length protein
Spitz, extracellular domain
Spleen tyrosine kinase
Squamous cell carcinoma antigen 1
Squash protein, CG 4711, full length protein
Squid A protein, full length
Squid S protein, full length
SQV-8, amino acids 150-349
Src homology 2 domain containing transforming protein D
SRY (sex determining region Y)-box 13
SRY (sex determining region Y)-box 4
SRY (sex determining region Y)-box 9
SSBP4; Single stranded DNA binding protein 4
SSEA-1/ alpha-(1,3)-fucosyltransferase / CD15
SSEA-3 (carbohydrate from 4-8 cell mouse embryos)
SSEA-4 (carbohydrate from human embryonal carcinoma)
STAM-binding protein
STAT1; Signal transducer and activator of transcription 1, 91kDa
STAT2; Signal transducer and activator of transcription 2, 113kDa
STAT3; Signal transducer and activator of transcription 3
STAT4; Signal transducer and activator of transcription 4
STAT5A; Signal transducer and activator of transcription 5A
STAT5B; Signal transducer and activator of transcription 5B
Steroidogenic factor 1
stromal cell surface marker
sucrase-isomaltase
Sulfotransferase family 1E, estrogen-preferring, member 1 [Homo sapiens]
SUMO aa76-86
SUMO-1
SUMO-2
Suppressor of cytokine signaling 2
Suppressor of fused (Su (fu))
SWI/SNF complex subunit SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
SYAP1; Synapse associated protein 1
sympathoadrenal marker
Synapse-associated protein 47 kDa; SAP47
Synapsin
Synaptic vesicle glycoprotein 2A; synaptic vesicles
synaptobrevin
Synaptotagmin
synaptotagmin 1, cytoplasmic domain
synaptotagmin B
synaptotagmin, cytoplasmic domain
Sync
Syntaxin
synuclein, alpha & beta
synuclein, gamma (breast cancer-specific protein 1) Peptide 1
synuclein-gamma
TAC-1
TADA2B; Transcriptional adaptor 2B
talin
talin (avian)
Talin carboxy terminus 534 amino acids
talinA (N-terminal)
Tango
Tannerella forsythia
TAR (HIV-1) RNA binding protein 2
Tau
TAX1BP1; Tax1 (human T-cell leukemia virus type I) binding protein 1
T-box 19
T-box transcription factor TBX19
T-box transcription factor TBX4
TBX19; T-box 19
TBX4; T-box 4
TCF25 Transcription Factors 25 (basic helix-loop-helix)
TEA domain family member 3
Telomeric Repeat Binding Factor 2 Peptide 1
tenascin
Tensin 1
Tensin 3
Tensin 4
TERF2; Telomeric repeat binding factor 2
TERF2IP; Telomeric repeat binding factor 2, interacting protein
tetraspanin large extracellular loop amino acids 111-217
TFAP2D; Transcription factor AP-2 delta
TGFb3, active domain
TGFb3, latent domain
TGIF1; TGFB-induced factor homeobox 1
TGIF2LX; TGFB-induced factor homeobox 2-like, X-linked
THAP domain containing 5
THAP domain containing 9
THAP domain-containing protein 11
THAP domain-containing protein 4
THAP10; THAP domain containing 10
Thyroid hormone receptor, alpha
Thyroid Stimulating Hormone, Beta Peptide 1
Thyroid Stimulating Hormone, beta Peptide 2
Titin
Topoisomerase I
topoisomerase I mitochondrial
TOX high mobility group box family member 3
TOX3; TOX high mobility group box family member 3
TP53; Tumor protein p53
Transcription elongation factor A (SII)-like 8
Transcription facotr RelB
Transcription factor Sp5
Transcription factor 25
Transcription factor AP-2 alpha
Transcription factor AP-2 beta
Transcription factor AP-2 gamma
Transcription factor CP2; Alpha-globin transcription factor CP2
Transcription factor elt-2
Transcription factor ETV6; Ets variant 6
Transcription factor Ovo-like 2
Transcription factor p65 or RELA
Transcription factor RelB
Transcription factor RFX3
Transcription factor SOX-9
Transcription factor Spi-C
Transcription Factors 24
Transcription Factors 25 (basic helix-loop-helix)
Transcription Factors AP-2 alpha (activating enhancer binding protein 2 alpha)
transcription factors E2F 6
transcription factors Ovo-like 2
transcription factors Spi-C
Transcriptional adaptor 3
Transcriptional enhancer factor TEF-3
Transcriptional regulator ERG
Transcriptional repressor NF-X1
transferrin receptor
Transgelin Peptide 1
transglutaminase, tissue
transitin
transketolase
Transthyretin
triadin
Trio
Tripartite motif containing 24
tRNA aspartic acid methyltransferase 1
tropomyosin
tropomyosin, chicken gizzard
tropomyosin, gizzard
tropomyosin, muscle
tropomyosin, recombinant human, isoform 5 and 4 fusion (hTM5/4) protein
tropomyosin, recombinant, isoform 5 and 4 fusion (hTM5/4) protein
troponin I, cardiac
troponin I, skeletal and cardiac
troponin T
troponin T, cardiac
troponin T, skeletal muscle specific
TRP protein (transient receptor potential)
truncated version of sry-a protein which contains amino acids 46 to 530 of sry-a
TSC22 domain family, member 1
TSC22D4; TSC22 domain family, member 4
TSLP
Tubulin
tubulin (alpha-)
tubulin (beta-)
Tubulin, beta
Tudor and KH domain containing
Tumbleweed
Tumor necrosis factor (ligand) superfamily, member 10
Tumor necrosis factor receptor superfamily member 9
Tumor protein p53
Tumor-associated Calcium Signal Transducer 2
tyrosine 3-monooxygenase or tryptophan 5-monooxygenase activation protein, beta polypeptide
tyrosine 3-monooxygenase or tryptophan 5-monooxygenase activation protein, epsilon polypeptide
tyrosine hydroxylase
Tyrosine-protein kinase Fes/Feline sarcoma oncogene
Tyrosine-protein kinase Fyn/ FYN oncogene related to SRC, FGR, YES
Tyrosine-protein ZAP-70
Tyrosyl-DNA Phosphodiesterase 2
Ubiquitin carboxyl-terminal hydrolase 14
Ubiquitin carboxyl-terminal hydrolase 16
Ubiquitin carboxyl-terminal hydrolase isozyme L1
Ubiquitin carboxyl-terminal hydrolase L3 (ubiquitin thiolesterase)
Ubiquitin carboxyl-terminal hydrolase L5
Ubiquitin Conjugating Enzyme E2C Peptide 1
Ubiquitin Conjugating Enzyme E2C Peptide 2
Ubiquitin Conjugating Enzyme E2E2
Ubiquitin Conjugating Enzyme E2L 6
Ubiquitin Conjugating Enzyme E2L 6; UBE2E1
Ubiquitin protein ligase E3A
Ubiquitin specific peptidase 7
Ubiquitin-conjugating enzyme E2 A
Ubiquitin-conjugating enzyme E2 B
Ubiquitin-conjugating enzyme E2 D1
Ubiquitin-conjugating enzyme E2 Q1
ubiquitin-conjugating enzyme E2, J1
Ubiquitin-conjugating enzyme E2C
ubiquitin-conjugating enzyme E2E 1
Ubiquitin-conjugating Enzymes E2B
Ubiquitin-like modifier activating enzyme 1
Ubiquitin-protein ligase E3A
UBQLN2; Ubiquilin 2
Ultrabithorax 5′ exon (107 amino acids)
Ultrabithorax protein
UNC-10, amino acids 1-144
Upstream transcription factor 2, c-fos interacting
Us9 (pseudorabies virus)
USF2; Upstream transcription factor 2, c-fos interacting
utrophin
utrophin aa 113-371
V_H_ATpase c-subunit
vasa
vasa protein
Vav 1 guanine nucleotide exchange factor
Vav 2 guanine nucleotide exchange factor
VCAM
VCAM-1
V-crk avian sarcoma virus CT10 oncogene homolog
VENTX homeobox protein
VENTX; VENT homeobox
VENTX; VENT homeobox
v-erb-b2 erythroblastic leukemia viral oncogene homolog Peptide 1
versican (hyaluronate-binding region)
Villin-like protein quail; 6B9
Vimentin
vimentin (Xenopus)
vimentin; radial and radial glial cell marker
vinculin
vinculin, meta-vinculin
visinin
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
Wash
Wash cDNA/GST fusion protein
Wasp
WDHD1; WD repeat and HMG-box DNA binding protein 1
Whamy
Windbeutel protein, N-terminal half
Wingless protein
wit
Wolf-Hirschhorn syndrome candidate 1
wound epithelium & transport / secretory cytoskeletal protein
wound epithelium & transport/secretory cell protein, 42 kDa
wrapper
Xenopus nuclear factor, xnf7
Xenotropic murine leukemia virus-related virus P12
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble Peptide 1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble Peptide 2
Yan Drosophila protein
YAP1 (YAP65 / Yes-associated protein 1)
Y-box-binding protein 3
YBX1; Y box binding protein 1
YBX2; Y box binding protein 2
YEATS domain containing 4
YEATS domain-containing 4
YEATS2; YEATS domain containing 2
YY1 transcription repressor protein
YY1 transcriptional repressor protein; Yin-Yang-1
YY2 Transcription Factors
ZBTB16; Zinc finger and BTB domain containing 16
ZBTB2; Zinc finger and BTB domain containing 2
ZBTB25; Zinc finger and BTB domain containing 25
ZBTB5; Zinc finger and BTB domain containing 5
ZBTB5; Zinc finger and BTB domain containing 5
ZCCHC7; Zinc finger, CCHC domain containing 7
ZEB2; Zinc finger E-box binding homeobox 2
Zeta-chain (TCR) associated protein kinase 70kDa
zeugmatin
ZFP3 zinc finger protein
ZFP41 zinc finger protein
ZFP90; ZFP90 zinc finger protein
ZFP92 zinc finger protein
ZFYVE19; Zinc finger, FYVE domain containing 19
ZFYVE20; Zinc finger, FYVE domain containing 20
Zic family member 2
ZIC1; Zic family member 1
ZIM2; Zinc finger, imprinted 2
zinc alpha-2-glycoprotein (ZAG)
Zinc finger and BTB domain containing 18
Zinc finger and BTB domain containing 21
Zinc finger and BTB domain containing 37
Zinc finger and BTB domain containing 39
Zinc finger and BTB domain containing 46
Zinc finger and BTB domain containing 7B
Zinc finger and BTB domain containing 7C
Zinc finger and BTB domain containing protein 32
Zinc finger and SCAN domain containing 2
Zinc finger and SCAN domain containing 25
Zinc finger and SCAN domain containing 5A
Zinc finger and SCAN domain containing 9
Zinc finger and SCAN domain-containing protein 26
Zinc finger and SCAN domain-containing protein 29
Zinc finger CCCH domain-containing protein 15
Zinc finger CCCH-type containing 7A
Zinc finger CCHC domain-containing protein 7
Zinc finger E-box binding homeobox 2
Zinc finger family member 783
Zinc finger protein 134
Zinc finger protein 140
Zinc finger protein 155
Zinc finger protein 157
Zinc finger protein 165
Zinc finger protein 169
Zinc finger protein 18
Zinc finger protein 189
Zinc finger protein 200
Zinc finger protein 202
Zinc finger protein 207
Zinc finger protein 222
Zinc finger protein 230
Zinc finger protein 239
Zinc finger protein 239; ZNF239
Zinc finger protein 24
Zinc finger protein 263
Zinc finger protein 264
Zinc finger protein 280A
Zinc finger protein 280D
Zinc finger protein 333
Zinc finger protein 341
Zinc finger protein 354A
Zinc finger protein 354B
Zinc finger protein 358
Zinc finger protein 384
Zinc finger protein 385B
Zinc finger protein 397
Zinc finger protein 408
Zinc finger protein 410
Zinc finger protein 428
Zinc finger protein 438
Zinc finger protein 446
Zinc finger protein 467; ZNF467
Zinc finger protein 485
Zinc finger protein 496
Zinc finger protein 521
Zinc finger protein 526
Zinc finger protein 543
Zinc finger protein 548
Zinc finger protein 549
Zinc finger protein 550
Zinc finger protein 554
Zinc finger protein 574
Zinc finger protein 581
Zinc finger protein 583
Zinc finger protein 584
Zinc finger protein 597
Zinc finger protein 608
Zinc finger protein 623
Zinc finger protein 648
Zinc finger protein 654
Zinc finger protein 654; melanoma-associated antigen
Zinc finger protein 683
Zinc finger protein 696
Zinc finger protein 697
Zinc finger protein 701
Zinc finger protein 75a
Zinc finger protein 770
Zinc finger protein 784
Zinc finger protein 792
Zinc finger protein 8
Zinc finger protein 800
Zinc finger protein 81
Zinc finger protein Gfi-1
Zinc finger protein ZFAT
Zinc finger protein ZFPM2
Zinc finger with KRAB and SCAN domains 7
Zinc finger with KRAB and SCAN domains 8
Zinc Finger, AN1-type Domain 6
Zinc finger, BED-type containing 1
Zinc finger, BED-type containing 3
Zinc finger, FYVE domain containing 20 (Rabenosyn-5)
Zinc finger, imprinted 2
Zinc finger, matrin-type 2
Zinc finger, matrin-type 4
Zinc finger, MYM-type 3
Zinc finger, ZZ-type containing 3
Zinc fingers and homeoboxes 1
Zinc fingers and homeoboxes 2
Zinc fingers and homeoboxes 3
ZKSCAN1; Zinc finger with KRAB and SCAN domains 1
ZKSCAN2; Zinc finger with KRAB and SCAN domains 2
ZKSCAN3; Zinc finger with KRAB and SCAN domains 3
ZMYM3; Zinc finger, MYM-type 3
ZNF157; Zinc finger protein 157
ZNF165; Zinc finger protein 165
ZNF174; Zinc finger protein 174
ZNF175; Zinc finger protein 175
ZNF18; Zinc finger protein 18
ZNF192; Zinc finger with KRAB and SCAN domains 8
ZNF197; Zinc finger protein 197
ZNF202; Zinc finger protein 202
ZNF207; Zinc finger protein 207
ZNF212; Zinc finger protein 212
ZNF217; Zinc finger protein 217
ZNF23; Zinc finger protein 23
ZNF230; Zinc finger protein 230
ZNF232; Zinc finger protein 232
ZNF277; Zinc finger protein 277
ZNF296; Zinc finger protein 296
ZNF324; Zinc finger protein 324
ZNF324; Zinc finger protein 324
ZNF354A; Zinc finger protein 354A
ZNF384; Zinc finger protein 384
ZNF397; Zinc finger protein 397
ZNF410; Zinc finger protein 410
ZNF444; Zinc finger protein 444
ZNF446; Zinc finger protein 446
ZNF48; Zinc finger protein 48
ZNF483; Zinc finger protein 483
ZNF488; Zinc finger protein 488
ZNF503-AS2; Zinc finger protein 503-AS2
ZNF556; Zinc finger protein 556
ZNF585B; Zinc finger protein 585B
ZNF639; Zinc finger protein 639
ZNF689; Zinc finger protein 689
ZNF783; Zinc finger family member 783
ZNF784; Zinc finger protein 784
ZNF830; Zinc finger protein 830
ZNF846; Zinc finger protein 846
ZNFX1; Zinc finger, NFX1-type containing 1
ZO-1 tight junction protein
ZSCAN12; Zinc finger and SCAN domain containing 12
ZSCAN2; Zinc finger and SCAN domain containing 2
ZSCAN21; Zinc finger and SCAN domain containing 21
ZSCAN22; Zinc finger and SCAN domain containing 22
ZSCAN23; Zinc finger and SCAN domain containing 23
ZSCAN31; Zinc finger and SCAN domain containing 31
ZSCAN5A; Zinc finger and SCAN domain containing 5A
ZUFSP; Zinc finger with UFM1-specific peptidase domain
Zw5
ZXD family zinc finger C
ZXDC; ZXD family zinc finger C
ZZZ3; Zinc finger, ZZ-type containing 3

Immunoglobulin superfamily

The immunoglobulin superfamily (IgSF) is a large group of cell surface and soluble proteins that are involved in the recognition, binding, or adhesion processes of cells. Molecules are categorized as members of this superfamily based on shared structural features with immunoglobulins (also known as antibodies); they all possess a domain known as an immunoglobulin domain or fold. Members of the IgSF include cell surface antigen receptors, co-receptors and co-stimulatory molecules of the immune system, molecules involved in antigen presentation to lymphocytes, cell adhesion molecules, certain cytokine receptors and intracellular muscle proteins. They are commonly associated with roles in the immune system. The sperm-specific protein Izumo, a member of the immunoglobulin superfamily, has also been identified as the only sperm membrane protein essential for sperm-egg fusion.

Immunoglobulin domains

Proteins of the IgSF possess a structural domain known as an immunoglobulin (Ig) domain. Ig domains are named after the immunoglobulin molecules. They contain about 70-110 amino acids and are categorized according to their size and function. Ig-domains possess a characteristic Ig-fold, which has a sandwich-like structure formed by two sheets of antiparallel beta strands. Interactions between hydrophobic amino acids on the inner side of the sandwich and highly conserved disulfide bonds formed between cysteine residues in the B and F strands, stabilize the Ig-fold. One end of the Ig domain has a section called the complementarity determining region that is important for the specificity of antibodies for their ligands.

Classification

The Ig like domains can be classified as IgV, IgC1, IgC2, or IgI.

Most Ig domains are either variable (IgV) or constant (IgC).

IgV: IgV domains with 9 beta strands are generally longer than IgC domains with 7 beta strands.
IgC1 and IgC2: Ig domains of some members of the IgSF resemble IgV domains in the amino acid sequence, yet are similar in size to IgC domains. These are called IgC2 domains, while standard IgC domains are called IgC1 domains.
IgI: Other Ig domains exist that are called intermediate (I) domains.

Members of the immunoglobulin superfamily

The Ig domain was reported to be the most populous family of proteins in the human genome with 765 members identified. Members of the family can be found even in the bodies of animals with a simple physiological structure such as poriferan sponges. They have also been found in bacteria, where their presence is thought to be due to horizontal gene transfer.

Members of the immunoglobulin superfamily
Molecule function/category Examples Description
Antigen receptors
  • Antibodies or immunoglobulins
  • T cell receptor chains
Antigen receptors found on the surface of T and B lymphocytes in all jawed vertebrates belong to the IgSF. Immunoglobulin molecules (the antigen receptors of B cells) are the founding members of the IgSF. In humans, there are five distinct types of immunoglobulinmolecule all containing a heavy chain with four Ig domains and a light chain with two Ig domains. The antigen receptor of T cells is the T cell receptor (TCR), which is composed of two chains, either the TCR-alpha and -beta chains, or the TCR-delta and gamma chains. All TCR chains contain two Ig domains in the extracellular portion; one IgV domain at the N-terminus and one IgC1 domain adjacent to the cell membrane.
Antigen presentingmolecules
  • Class I MHC
  • Class II MHC
  • beta-2 microglobulin
The ligands for TCRs are major histocompatibility complex (MHC) proteins. These come in two forms; MHC class I forms a dimer with a molecule called beta-2 microglobulin (β2M) and interacts with the TCR on cytotoxic T cells and MHC class II has two chains (alpha and beta) that interact with the TCR on helper T cells. MHC class I, MHC class II and β2M molecules all possess Ig domains and are therefore also members of the IgSF.
Co-receptors
  • CD4
  • CD8
  • CD19
Co-receptors and accessory molecules: Other molecules on the surfaces of T cells also interact with MHC molecules during TCR engagement. These are known as co-receptors. In lymphocyte populations, the co-receptor CD4is found on helper T cells and the co-receptor CD8 is found on cytotoxic T cells. CD4 has four Ig domains in its extracellular portion and functions as a monomer. CD8, in contrast, functions as a dimer with either two identical alpha chains or, more typically, with an alpha and beta chain. CD8-alpha and CD8-beta each has one extracellular IgV domain in its extracellular portion. A co-receptor complex is also used by the BCR, including CD19, an IgSF molecule with two IgC2-domains.
Antigen receptor accessory molecules
  • CD3-γ, -δ and -ε chains
  • CD79a and CD79b
A further molecule is found on the surface of T cells that is also involved in signaling from the TCR. CD3 is a molecule that helps to transmit a signal from the TCR following its interaction with MHC molecules. Three different chains make up CD3 in humans, the gamma chain, delta chain and epsilon chain, all of which are IgSF molecules with a single Ig domain.Similar to the situation with T cells, B cells also have cell surface co-receptors and accessory molecules that assist with cell activation by the B Cell Receptor (BCR)/immunoglobulin. Two chains are used or signaling, CD79a and CD79b that both possess a single Ig domain.
Co-stimulatory or inhibitory molecules
  • CD28
  • CD80 and CD86 (also known as B7.1 and B7.2 molecules)
Co-stimulatory or inhibitory molecules: Co-stimulatory and inhibitory signaling receptors and ligands control the activation, expansion and effector functions of cells. One major group of IgSF co-stimulatory receptors are molecules of the CD28 family; CD28, CTLA-4, program death-1 (PD-1), the B- and T-lymphocyte attenuator (BTLA, CD272), and the inducible T-cell co-stimulator (ICOS, CD278);[7] and their IgSF ligands belong to the B7 family; CD80 (B7-1), CD86 (B7-2), ICOS ligand, PD-L1 (B7-H1), PD-L2 (B7-DC), B7-H3, and B7-H4 (B7x/B7-S1).[8]
Receptors on Natural killer cells
  • Killer-cell immunoglobulin-like receptors (KIR)
Receptors on Leukocytes
  • Leukocyte immunoglobulin-like receptors (LILR)
IgSF CAMs
  • NCAMs
  • ICAM-1
  • CD2 subset
  • Type IIa and Type IIb RPTPs, described in Receptor tyrosine kinases/phosphatases subsection below
  • CD2 subset of IgSF represented large group of homologous cell adhesion molecules (CAMs), includes CD2, CD58, CD48, CD150, CD229 and CD244.[9][10][11]
Cytokine receptors
  • Interleukin-6 receptor
  • Colony stimulating factor 1 receptor
Growth factor receptors
  • Platelet-derived growth factor receptor(PDGFR)
  • Mast/stem cell growth factor receptor precursor (SCFR, c-kit, CD117 antigen)
Receptor tyrosine kinases/phosphatases
  • Tyrosine-protein kinase receptor Tie-1 precursor
  • Type IIa and Type IIb Receptor protein tyrosine phosphatases(RPTPs), including, but not limited to, PTPRM, PTPRK, PTPRU, PTPRD, PTPRF
Ig binding receptors
  • polymeric immunoglobulin receptor (PIGR)
  • Some Fc receptors
Others
  • CD147
  • CD90
  • CD7
  • Butyrophilins (Btn)
  • Titin

 

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